Mail Them Pro - description from Softdepia.com:
If you need a program for mass mailings and mailing lists management, Mail Them Pro is what you are looking for!
This program is designed for mass mailings and e-mail extraction from newsgroups. It has its own high-performance built-in SMTP server, so you don't need to use your ISP's SMTP server for direct email delivery. SMTP bulk email server possesses almost 100 simultaneous threads. Watch the process of sending, view the detailed logs and reduce the number of non-delivery reports to save your bandwidth.
Mail Them Pro is easily customizable software and it supports handling for subscribe and unsubscribe requests and bounced messages. Spam Check tool would check your e-mail content against the most popular spam filter Spamassassin and would recommend you how to avoid spam filters and bulk email folders.
The program features sending HTML pages with embedded graphics and mixed emails that contain both plain text and HTML. Mail Them Pro supports importing emails from Windows Address Book, Excel, Access, MySQL and MS SQL Server.
Mail Them Pro is a "Free to try" program. You can download and try it for an evaluation period.